Appetite Suppressant & Dopaminergic Fat Burner Tesofensine works by modulating neurotransmitters like dopamine, norepinephrine, and serotonin—cutting appetite and increasing energy. Originally studied for Parkinson’s and Alzheimer’s, it became a breakthrough weight loss agent with 10–12% body fat reduction in trials. Ideal for those plateauing or needing help with portion control and food-driven urges.